1H-Imidazole, 2-phenyl-5-(trifluoromethyl)-

1H-Imidazole, 2-phenyl-5-(trifluoromethyl)- - Names and Identifiers

Name	2-Phenyl-4-(trifluoromethyl)-1H-imidazole
Synonyms	2-Phenyl-4-(trifluoromethyl)-1H-imidazole 2-Phenyl-5-(trifluoroMethyl)-1H-iMidazole 2-phenyl-4-(trifluoromethyl)-1H-imidazole 2-phenyl-5-(trifluoromethyl)-1H-imidazole 1H-imidazole, 2-phenyl-4-(trifluoromethyl)- 1H-Imidazole, 2-phenyl-5-(trifluoromethyl)- 2-Phenyl-4-trifluoromethyl-1,6-dihydro-pyrimidine
CAS	33469-36-2
InChI	InChI=1/C10H7F3N2/c11-10(12,13)8-6-14-9(15-8)7-4-2-1-3-5-7/h1-6H,(H,14,15)

1H-Imidazole, 2-phenyl-5-(trifluoromethyl)- - Physico-chemical Properties

Molecular Formula	C10H7F3N2
Molar Mass	212.17
Density	1.327
Melting Point	212-213 °C
Boling Point	336.8°C at 760 mmHg
Flash Point	157.5°C
Vapor Presure	0.000214mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.517

1H-Imidazole, 2-phenyl-5-(trifluoromethyl)- - Introduction

2-Phenyl-4-(trifluoromethyl)-1H-imidazole is an organic compound with the chemical formula C10H7F3N2. It is white to yellow crystals with a special aroma.

This compound is commonly used in pharmaceutical synthesis and research. Its main use is as a protein kinase inhibitor and an intermediate for anticancer drugs. Because of its special structure and function, it is also widely used in the field of organic synthesis.

The method of preparing 2-Phenyl-4-(trifluoromethyl)-1H-imidazole can be achieved in a variety of ways. A common method is to react 2-phenyl -4-dimethoxymethylimidazole with trifluoromethyl benzyl bromide to form the product which is treated with acid to give the target compound.

Regarding safety information, 2-Phenyl-4-(trifluoromethyl)-1H-imidazole is an organic compound and should be used in accordance with safe operating procedures. It is an irritating substance and is irritating to the eyes and skin, so contact with eyes and skin should be avoided. At the same time, ventilation measures should be taken during use to avoid inhaling its steam. It should also be stored in a sealed container to avoid contact with oxidants and high temperatures. If necessary, it is recommended to operate under the guidance of a chemical professional.

Last Update：2024-04-09 21:11:58